Table 4.
BM protein localization in the human cochlea.
| Protein | STV | RM | SL | IDC | OS | IS | bm | Slim | OSL | OC (IHC+OHC) |
|---|---|---|---|---|---|---|---|---|---|---|
| Collagen IVα2/ |
PV & PN +++ |
+++ | PV+++ | ++ | ++ | + | + | ++ | ++ | − |
| Nidogen/ | PV & PN +++ |
+++ | PV+++ | ++ | ++ | + | + | ++ | +++ | − |
| Tenascin-C/ | − | − | − | − | − | − | +++ | − | +++ | − |
| Laminin-β-2/ | PV & PN +++ |
+++ | PV +++ |
+ | + | + | ++ | ++ | +++ | − |
| αDystroglycan | +++ | +++ | − | +++ | +++ | ++ | − | − | +++ | − |
Legend: OC; Organ of Corti; IHC:inner hair cells; OHC:outer hair cells; STV: stria vascularis; Reissner’s membrane: RM; Spiral ligament: SL; Interdental cells IDC; Outer sulcus:OS; Inner sulcus: IC, basilar membrane: bm; Spiral limbus: Slim; Osseous spiral lamina:OSL; PV: perivascular; PN: perineural
−= not detected
+= faintly immunoreactive
++= immunoreactive
+++= highly immunoreactive