Table I.
Spot # | Gene symbol | Gene name | Fold changea |
---|---|---|---|
1 | ANXA5 | Annexin A5 | 1.24 |
2 | ATM | Ataxia telangiectasia mutated | 1.57 |
3 | BAX | BCL2-associated X protein | 1.41 |
4 | BCL2L1 | BCL2-like 1 | 1.43 |
5 | BCL2L2 | BCL2-like 2 | 0.91 |
6 | CASP1 | Caspase 1, apoptosis-related cysteine protease | 1.27 |
7 | CASP 10 | Caspase 10, apoptosis-related cysteine protease | 1.21 |
8 | CASP8 | Caspase 8, apoptosis-related cysteine protease | 1.54 |
9 | CAT | Catalase | 1.50 |
10 | CCNC | Cyclin C | 1.59 |
11 | CCND1 | Cyclin Dl (PRAD1: parathyroid adenomatosis 1) | 1.23 |
12 | CCNG1 | Cyclin G 1 | 1.78 |
13 | CDKN1A | Cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.96 |
14 | CHEK2 | CHK2 checkpoint homolog (S. pombe) | 1.06 |
15 | CRYAB | Crystallin, alpha B | 1.01 |
16 | CSF2 | Colony stimulating factor 2 | 1.80 |
17 | CYP1A1 | Cytochrome P450, family 1, subfamily A, | 1.34 |
18 | CYP1B1 | Cytochrome P450, family 1, subfamily B, | 1.84 |
19 | CYP2E1 | Cytochrome P450, family 2, subfamily E, | 1.43 |
20 | CYP7A1 | Cytochrome P450, family 7, subfamily A, | 1.57 |
217 | CYP7B1 | Cytochrome P450, family 7, subfamily B, | 1.27 |
22 | DDB1 | Damage-specific DNA binding protein 1, | 1.35 |
23 | DDIT3 | DNA-damage-inducible transcript 3 | 1.46 |
24 | DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 1.55 |
25 | DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 | 1.55 |
26 | E2F1 | E2F transcription factor 1 | 1.17 |
27 | EGR1 | Early growth response 1 | 1.51 |
28 | EPHX2 | Epoxide hydrolase 2, cytoplasmic | 1.16 |
29 | ERCC1 | Excision repair cross-complementing group 1 | 1.38 |
30 | ERCC3 | Excision repair cross-complementing group 3 | 1.68 |
31 | ERCC4 | Excision repair cross-complementing group 4 | 2.10 |
32 | ERCC5 | Excision repair cross-complementing group 5 | 1.94 |
33 | FMO1 | Flavin containing monooxygenase 1 | 1.54 |
34 | FMO5 | Flavin containing monooxygenase 5 | 0.94 |
35 | GADD45A | Growth arrest and DNA-damage-inducible, alpha | 1.40 |
36 | GADD45B | Growth arrest and DNA-damage-inducible, beta | 1.27 |
37 | GPX1 | Glutathione peroxidase 1 | 1.03 |
38 | GSR | Glutathione reductase | 1.23 |
39 | GSTM3 | Glutathione S-transferase M3 (brain) | 1.08 |
40 | HMOX1 | Heme oxygenase (decycling) 1 | 2.07 |
41 | HMOX2 | Heme oxygenase (decycling) 2 | 3.14 |
42 | HSF1 | Heat shock transcription factor 1 | 1.36 |
43 | HSPH1 | Heat shock 105 kDa/110 kDa protein 1 | 1.13 |
44 | HSPA1A | Heat shock 70 kDa protein 1A | 1.40 |
45 | PTGS1 | Prostaglandin-endoperoxide synthase 1 | 1.11 |
46 | HSPA1L | Heat shock 70 kDa protein 1-like | 1.47 |
47 | HSPA2 | Heat shock 70 kDa protein 2 | 1.12 |
48 | HSPA4 | Heat shock 70 kDa protein 4 | 1.30 |
49 | HSPA5 | Heat shock 70 kDa protein 5 | 1.80 |
50 | HSPA6 | Heat shock 70 kDa protein 6 | 1.26 |
51 | HSPA8 | Heat shock 70 kDa protein 8 | 1.18 |
52 | HSPA9B | Heat shock 70 kDa protein 9B | 1.07 |
53 | HSPB1 | Heat shock 27 kDa protein 1 | 0.83 |
54 | HSPCA | Heat shock 90 kDa protein 1, alpha | 1.04 |
55 | HSPCB | Heat shock 90 kDa protein 1, beta | 0.92 |
56 | HSPD1 | Heat shock 60 kDa protein 1 | 1.43 |
57 | HSPE1 | Heat shock 10 kDa protein 1 | 2.35 |
58 | IGPBP6 | Insulin-like growth factor binding protein 6 | 1.19 |
59 | IL18 | Interleukin 18 | 1.77 |
60 | IL1A | Interleukin 1, alpha | 1.27 |
61 | IL1B | Interleukin 1, beta | 1.03 |
62 | IL6 | Interleukin 6 (interferon, beta 2) | 0.81 |
63 | LTA | Lymphotoxin alpha | 0.81 |
64 | MDM2 | Mdm2, transformed 3T3 cell double minute 2, | 1.31 |
65 | MIF | Macrophage migration inhibitory factor | 1.45 |
66 | PRDX1 | Peroxiredoxin 1 | 1.26 |
67 | PRDX2 | Petoxiredoxin 2 | 1.25 |
68 | MT2A | Metallothionein 2A | 1.21 |
69 | NFKB1 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 0.85 |
70 | NFKBIA | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 1.46 |
71 | NOS2A | Nitric oxide synthase 2A | 1.33 |
72 | PCNA | Proliferating cell nuclear antigen | 0.92 |
73 | GDF15 | Growth differentiation factor 15 | 1.76 |
74 | POR | P450 (cytochrome) oxidoreductase | 1.48 |
75 | PTGS2 | Prostaglandin-endoperoxide synthase 2 | 1.16 |
76 | RAD23A | RAD23 homolog A (S. cerevisiae) | 1.10 |
77 | RAD50 | RAD50 homolog (S. cerevisiae) | 1.03 |
78 | CCL21 | Chemokine (C-C motif) ligand 21 | 1.40 |
79 | CCL3 | Chemokine (C-C motif) ligand 3 | 1.25 |
80 | CCL4 | Chemokine (C-C motif) ligand 4 | 1.34 |
81 | CXCL10 | Chemokine (C-X-C motif) ligand 10 | 1.23 |
82 | SERPINE1 | Serine (or cysteine) proteinase inhibitor | 1.19 |
83 | SOD1 | Superoxide dismutase 1 | 0.92 |
84 | SOD2 | Superoxide dismutase 2, | 0.88 |
85 | TNF | Tumor necrosis factor | 1.14 |
86 | TNFRSF1A | TNF receptor superfamily, member 1A | 0.91 |
87 | TNFSF10 | TNF (ligand) superfamily, member 10 | 1.38 |
88 | FASLG | Fas ligand (TNF superfamily, member 6) | 0.92 |
89 | TP53 | Tumor protein p53 (Li-Fraumeni syndrome) | 1.58 |
90 | TRADD | TNFRSF1A-associaled via death domain | 1.03 |
91 | UGT1A10 | UDP glycosyltransferase 1 family | 1.03 |
92 | UNG | Uracil-DNA glycosylase | 0.77 |
93 | XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 | 1.19 |
94 | XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 | 1.21 |
95 | XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | 1.19 |
96 | XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 | 1.14 |
Fold Changes represent the ratio of spot density of treated samples divided those by control. The density values were normalized to beta actin before obtaining the fold changes.