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. Author manuscript; available in PMC: 2009 Oct 6.
Published in final edited form as: Biochemistry. 2008 Jun 3;47(26):6883–6894. doi: 10.1021/bi800519a

FIGURE 7.

FIGURE 7

Proposed model of the Tetrahymena ribozyme transition state from functional data (ref 10 and references cited therein and this work). Bonds made and broken at the transition state are represented by dashed lines. Hydrogen bonds are represented by hashed lines. Functional contacts between metal ions and their ligands are represented by solid dots of the same color of the metal ion; contacts from this work are in larger font.