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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Pediatr Res. 2009 Aug;66(2):162–167. doi: 10.1203/PDR.0b013e3181aabd66

Figure 6. Exogenous SP-A reduced inflammatory cell influx and partially restored the NO response in Ureaplasma-inoculated SP-A−/− mice.

Figure 6

SP-A−/− mice were inoculated intratracheally with 106 CCU Ureaplasma ± 100 µg purified human SP-A and lungs harvested after 6, 24 or 48h. Total and differential cell counts were performed. Nitrite in BAL was measured after nitrate was reduced to nitrite with nitrate reductase, U. parvum inoculation alone, black bars; U. parvum plus SP-A inoculation, white bars. Data are expressed as the means ± SE of the total number of inflammatory cells (A), neutrophils (B), or, total NO (C). *p<0.05 vs Ureaplasma-inoculated SPA−/− 24h post-inoculation.