Figure 2. WBC and CEP levels and relative tumor necrosis detected in G-CSF-R−/− mice following treatment with OXi-4503.
(A) CEP levels, and (B) WBC counts were evaluated at baseline, 4 and 24 hours after OXi-4503 treatment, in non-tumor bearing G-CSF-R−/− mice (filled bars) and their respective wt controls (open bars). (C) Relative necrosis in tumor sections from both G-CSF-R−/− and wt control mice following treatment with OXi-4503 (bar=100μm). (D) Quantitative data on the percentage of necrosis area from all tumor area.