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. 2009 Jun 9;104(6):751–760. doi: 10.1007/s00395-009-0038-y

Table 4.

Changes in pCa50

ΔpCa50 WT L29Q
Before/after cTnC-exchange +0.06 ± 0.044 +0.06 ± 0.030
Before/after cTnC-exchange + PPlc −0.04 ± 0.030 −0.08 ± 0.030
PPlc, before/after PKA +0.18 ± 0.004 +0.20 ± 0.022

Table 4 summarizes the changes in pCa50 induced in skinned fibers (1.) by exchange with the recombinant hcTnCs (WT/L29Q), (2.) by exchange with the recombinant cTnCs and additional treatment with phosphatase, and (3.) the ΔpCa50 induced by incubation of the phosphatase-treated, exchanged fibers with PKA