Table 1.
Clinical and demographic characteristics of the study population
| Characteristic | All (n = 139) | Serum IS |
P Value | ||
|---|---|---|---|---|---|
| 1st Tertile (n = 46) | 2nd Tertile (n = 46) | 3rd Tertile (n = 47) | |||
| Age (yr) | 67 ± 12 | 68 ± 10 | 66 ± 14 | 67 ± 13 | 0.798 |
| Male gender [n (%)] | 84 (60) | 26 (56) | 31 (67) | 27 (57) | 0.496 |
| Body mass index (kg/m2) | 28 ± 6 | 28 ± 6 | 30 ± 7 | 27 ± 5 | 0.107 |
| Diabetes mellitus [n (%)] | 58 (42) | 23 (50) | 21 (46) | 14 (30) | 0.114 |
| Smoking habit [n (%)] | 55 (40) | 15 (33) | 24 (54) | 16 (34) | 0.068 |
| Presence of CVD [n (%)] | 45 (32) | 16 (35) | 10 (22) | 19 (40) | 0.143 |
| Systolic arterial pressure (mmHg) | 153 ± 26 | 148 ± 25 | 156 ± 28 | 155 ± 26 | 0.298 |
| Diastolic arterial pressure (mmHg) | 81 ± 12 | 80 ± 12 | 83 ± 12 | 80 ± 13 | 0.278 |
| CKD stage [n (%)] | <0.0001 | ||||
| 2 | 11 (8) | 11 (24) | 0 (0) | 0 (0) | |
| 3 | 37 (26.5) | 24 (52.5) | 13 (28) | 0 (0) | |
| 4 | 37 (26.5) | 6 (13) | 27 (59) | 4 (8) | |
| 5 | 10 (7) | 2 (4) | 3 (6.5) | 5 (11) | |
| 5D | 44 (32) | 3 (6.5) | 3 (6.5) | 38 (81) | |
Data are expressed as mean ± SD or, for binary variables, number (frequency). Tertiles are ordered from low serum IS levels to high levels: 1st tertile <0.26 mg/100 ml; 2nd tertile ≥0.26 mg/100 ml and <0.76 mg/100 ml; and 3rd tertile ≥0.76 mg/100 ml.