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. Author manuscript; available in PMC: 2009 Oct 6.
Published in final edited form as: Carbohydr Res. 2007 Sep 7;342(18):2745–2749. doi: 10.1016/j.carres.2007.08.025

Fig. 2.

Fig. 2

Effect of fructosazines on cytokine release by Jurkat cells.

Fructosazines (A) and D-GlcN (B) reduce IL-2 production by Jurkat cells in a dose-dependent fashion. Cells were activated with PHA in the presence of various doses of fructosazines or D-GlcN. Fructosazines caused a dramatic reduction in IL-2 production by cells. As these data illustrate, fructosazines are substantially more effective in blocking IL-2 release than its parent compound, D-GlcN. Cell viability was also measured in the presence of fructosazines (C) and D-GlcN (D). In all cases, there was no significant effect of these compounds or of the stimulatory PHA molecules on the viability of Jurkat cells.