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Expression of FGF23 mRNA in MLO-A5 cells. A) Elevated expression in response to hydroxylapatite in 3D collagen matrix. The dashed line shows the control level without hydroxylapatite. B) Reduced FGF23 expression by pertussis toxin (100 ng/ml, and 500 ng/ml) in 3D collagen matrix in the presence of hydroxylapatite.
