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FGF23-linked parameters employed in the study.
| FGF23 pathways | Effect | Remark | Value |
|---|---|---|---|
| General | Rate of FGF23 degradation | 0.8 h−1 | |
| Reference FGF23 concentration | 0.03 ng/ml | ||
| I (P to FGF23) | stimulatory | Michaelis constant | 0.03 mg/ml |
| II (calcitriol to FGF23) | stimulatory | Michaelis constant | 0.038 ng/ml |
| III (FGF23 to calcitriol) | inhibitory | Michaelis constant | 0.03 ng/ml |
| IV (FGF23 to PTH) | inhibitory | Michaelis constant | 0.03 ng/ml |
| V (FGF23 to P) | stimulatory | Michaelis constant | 0.03 ng/ml |
