Table 1.
Characteristics of study participants.
| Mayo Clinic |
Duke University |
||||||
|---|---|---|---|---|---|---|---|
| All cases (N=396) | Controls (N=469) | p-value | All cases (N=534) | Controls (N=568) | p-value | ||
| Age, years | Mean (S.D.) | 59.8 (13.3) | 60.1 (13.0) | 0.82 | 54 (11.5) | 54.7 (12.2) | 0.35 |
| Race | Caucasian | 375 (97.2) | 462 (98.5) | 0.73 | 444 (83.3) | 479 (84.3) | 0.77 |
| African American | 3 (0.8) | 2 (0.5) | 70 (13.1) | 74 (13.0) | |||
| Hispanic | 3 (0.8) | 3 (0.8) | 5 (0.9) | 5 (0.09) | |||
| Native American | 0 (0.0) | 0 (0.0) | 5 (0.9) | 6 (1.1) | |||
| Asian | 2 (0.5) | 1 (0.2) | 6 (1.1) | 2 (0.4) | |||
| Other | 3 (0.8) | 1 (0.2) | 3 (0.6) | 2 (0.4) | |||
| Body mass index, kg/m2 | <23 | 79 (20.7) | 110 (25.1) | 0.02 | 132 (25.4) | 139 (25.2) | 0.29 |
| 23–26 | 88 (23.1) | 121 (27.6) | 117 (22.5) | 124 (22.5) | |||
| 26–29 | 98 (25.7) | 112 (25.6) | 106 (20.4) | 136 (24.7) | |||
| ≥29 | 116 (30.4) | 95 (21.7) | 165 (31.7) | 152 (27.6) | |||
| Oral contraceptive use | Never | 176 (47.6) | 166 (38.4) | <0.001 | 182 (34.7) | 181 (32.2) | 0.36 |
| 1–48 months | 98 (26.5) | 92 (21.3) | 158 (30.2) | 160 (28.5) | |||
| ≥48 months | 96 (25.9) | 174 (40.3) | 184(35.1) | 221 (39.3) | |||
| Parity, n/age at first birth, years | Nulliparous | 70 (18.3) | 66 (15.0) | 0.07 | 113 (21.2) | 73 (12.9) | 0.003 |
| 1–2/≤20 years | 29 (7.6) | 25 (5.7) | 73 (13.7) | 69 (12.1) | |||
| 1–2/>20 years | 103 (26.9) | 131 (29.8) | 193 (36.2) | 233 (41) | |||
| ≥3/≤20 years | 73 (19.1) | 64 (14.5) | 81 (15.2) | 93 (16.4) | |||
| ≥3/>20 years | 108 (28.2) | 154 (35.0) | 73 (13.7) | 100 (17.6) | |||
| Ovarian cancer family history | Yes | 51 (13.3) | 33 (7.4) | 0.01 | 42 (7.9) | 25 (4.4) | 0.02 |
| No | 333 (86.7) | 411 (92.6) | 492 (92.1) | 543 (95.6) | |||
| Education achieved | No diploma | 25 (6.9) | 19 (4.3) | <0.001 | 53 (9.9) | 69 (12.1) | 0.40 |
| High school | 136 (37.4) | 117 (26.4) | 153 (28.7) | 149 (26.2) | |||
| Post high school | 203 (55.8) | 307 (69.3) | 327 (61.4) | 350 (61.6) | |||
Data are counts (percentage) unless otherwise indicated. Counts may not total to 1967 subjects due to missing data for some variables. P-values are from t-test for continuous variables and Chi square test for categorical variables; family history indicates first or second degree relative; bold indicates p≤ 0.05.