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. Author manuscript; available in PMC: 2009 Oct 6.
Published in final edited form as: Chem Res Toxicol. 2009 Jan;22(1):52–63. doi: 10.1021/tx800048m

Figure 1.

Figure 1

Ribbon and surface representation of ERα in complex with the agonist diethylstilbestrol (a) (PDB code: 3ERD), closed conformation, and with a dihydrobenzoxathiin SERM (b) (PDB code: 1XPC), open conformation. H12 (red) exhibits different orientations in the two complexes.