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. 2007 Nov 16;34(2):141–148. doi: 10.1007/s12031-007-9018-6

Figure 4.

Figure 4

AMPA and glycine evoked currents on hippocampal neurons transfected with ScFv-Geph2-EGFP-NLS A. Upper traces: current responses evoked at −40 mV by application of AMPA (50 μM; open bars) in nontransfected (left) and scFv-Gephyrin-NLS transfected neurons present in the same dish (right). Lower traces: current responses evoked at −40 mV by application of glycine (100 μM; closed bars) in nontransfected (left) and scFv-Gephyrin-NLS transfected neurons present in the same dish (right). B. Dose–response curves for glycine-evoked currents obtained in hippocampal neurons transfected with EGFP (open triangles) or with scFv-Gephyrin-NLS (scFv-Gephyrin, closed triangles). Open circles refer to current responses obtained from nontransfected cells present with scFv-Gephyrin-NLS transfected neurons on the same dish. Each point is the average of 9–20 individual responses