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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2008 Nov 27;239(2):130–136. doi: 10.1016/j.taap.2008.11.011

Figure 5. Treatment of WI-38 cells with MMAIII activates quinone reductase promoter confirming ARE regulation.

Figure 5

WI-38 cells were transiently transfected with rat quinone reductase (QR) promoter fusion construct (Hintze et al., 2003b) and exposed to MMAIII at the concentrations indicated. Similar to the results for TrxR1 construct, cells treated with 2 μM MMAIII increased activation of the promoter of QR (*, p<0.05).