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. Author manuscript; available in PMC: 2009 Oct 7.
Published in final edited form as: Neuropsychopharmacology. 2009 Jan 21;34(7):1710–1720. doi: 10.1038/npp.2008.228

Figure 2.

Figure 2

Haloperidol-induced histone H3 hosphorylation is prevented by blockade of A2ARs. Wild type mice were treated with haloperidol alone, or in combination with the A2AR antagonist KW6002 (injected 5 min prior to haloperidol) and perfused 15 min later. Quantification of phospho-Ser10-acetyl-Lys14-histone H3 (P-AcH3) immunoreactive neurons in the dorsomedial (DM) and dorsolateral (DL) striata of mice treated with vehicle (Veh), haloperidol (Hal), or haloperidol plus KW6002 (* p < 0.05, *** p < 0.001 vs. vehicle; °°p < 0.01 vs. Hal).

HHS Vulnerability Disclosure