Table 2.
Crude and adjusted odds ratios (OR) for the association between diagnosed current asthma and total IgE (log10 transformed) stratified by positive specific IgE tests.
| Stratum | OR (95% CI) for asthma for a 10-fold increase in total IgE | |||
|---|---|---|---|---|
| Unadjusted | P-value† | Adjusted‡ | P-value† | |
| All subjects | 2.01 (1.58, 2.56) | -- | 2.18 (1.66, 2.87) | -- |
| At least 1 positive specific IgE | 0.005 | 0.005 | ||
| No | 1.06 (0.71, 1.58) | 1.11 (0.72, 1.71) | ||
| Yes | 2.09 (1.48, 2.95) | 2.41 (1.62, 3.60) | ||
| Number of positive specific IgE | 0.035 | 0.093 | ||
| 0 | 1.06 (0.71, 1.58) | 1.11 (0.72, 1.71) | ||
| 1–6 | 1.57 (1.07, 2.29) | 1.81 (1.18, 2.78) | ||
| 7–15 | 1.84 (1.18, 2.86) | 2.14 (1.21, 3.78) | ||
| Sum of specific IgE | 0.019 | 0.018 | ||
| All at LLOD | 1.06 (0.71, 1.58) | 1.11 (0.72, 1.71) | ||
| < Median [3.76 – 12.07] | 1.24 (0.76, 2.02) | 1.47 (0.88, 2.45) | ||
| > Median [12.08 – 2468] | 2.04 (1.30, 3.20) | 2.31 (1.40, 3.83) | ||
†
P-value for the test that the association between asthma and total IgE differs across categories
‡
Adjusted for age, gender, race, education, poverty, BMI, and serum cotinine.