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. 2009 Oct 14;4(10):e7448. doi: 10.1371/journal.pone.0007448

Table 1. Fractions of MHC class I and II ligand-containing proteins that belong to a selection of GO cellular component terms.

Gene Ontology Term Fraction, MHCI Corrected P-value, MHCI Fraction, MHCII Corrected P-value, MHCII Fraction, background
cell 96.8% 2.05E-13 92.4% 0.443 91.1%
intracellular 86.7% 3.07E-60 61.6% 0.938 65.3%
organelle 69.3% 1.23E-33 49.2% 0.861 51.5%
cytoplasm 62.4% 8.88E-52 52.4% 4.42E-03 40.2%
nucleus 39.9% 3.57E-15 10.8% 1 28.8%
macromolecular complex 32.6% 2.94E-54 25.4% 8.58E-04 14.6%
cytosol 17.7% 3.88E-52 12.4% 1.42E-03 5.3%
organelle lumen 15.1% 1.04E-20 5.9% 0.861 7.0%
ribonucleoprotein complex 10.6% 7.69E-26 1.6% 0.995 3.6%
cytosolic ribosom 4.1% 3.93E-35 1.6% 0.125 0.4%
membrane 33.5% 1 58.9% 9.68E-05 42.8%
plasma membrane 14.5% 1 40.5% 1.81E-09 19.9%
extracellular region 5.6% 1 22.7% 2.27E-04 11.8%
integral to plasma membrane 4.5% 1 22.2% 1.04E-09 7.0%
vesicle 4.1% 0.023 14.1% 7.09E-10 2.8%
vacoule 1.5% 0.475 10.3% 6.25E-10 1.4%
lysosome 1.2% 0.705 9.2% 2.12E-09 1.2%
pigment granule 2.3% 1.65E-09 8.6% 1.27E-13 0.5%
melanosome 2.3% 1.65E-09 8.6% 1.27E-13 0.5%

Fractions and the corresponding p-values for some of the most significantly enriched terms are marked in bold. The p-values have been corrected for multiple testing by the Benjamini & Hochberg correction method.