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| Type | Enzyme | Location | Monophenol oxidase activity | Diphenol oxidase activity | o-aminophenol oxidase activity | Function | Occurrence |
| I | MelD2 | Intracellular | + | + | − | Detoxification | Universal |
| II | MelC2 | Extracellular | + | + | + | Competition? | Sporadic |
| III | GriF | Intracellular | − | + | + | Biosynthesis | Rare |
