Table 2.

Birth-related characteristics and neuroblastoma

	Controls n = 1681	Neuroblastoma
		All neuroblastoma			MYCN non-amplified			MYCN amplified
		n = 191	OR1	95% CI2	n = 144	OR	95% CI	n = 35	OR	95% CI
Maternal age at birth (year)
<25	163	35	2.3	(1.5–3.6)	25	2.2	(1.3–3.7)	5	1.7	(0.6–4.7)
25–34	1235	124	1.0	reference	97	1.0	reference	22	1.0	reference
35 +	283	32	0.9	(0.5–1.4)	22	0.8	(0.5–1.3)	8	1.2	(0.5–2.8)
Birth weight (gram)c
<2500	94	15	1.8	(0.8–3.8)	9	1.6	(0.6–4.0)	5	2.2	(0.5–11)
2500–2999	304	39	1.3	(0.8–2.1)	34	1.6	(0.9–2.6)	5	1.1	(0.3–3.4)
3000–3499	671	62	1.0	reference	48	1.0	reference	9	1.0	reference
3500–3999	464	53	1.2	(0.8–1.8)	41	1.2	(0.7–1.9)	11	1.8	(0.7–4.5)
≥4000	147	21	1.6	(0.9–2.8)	12	1.2	(0.6–2.4)	5	2.6	(0.8–8.2)
Birth weight in quintiles (gram)c
<2930	334	50	1.4	(0.8–2.3)	40	1.8	(1.0–3.2)	9	1.3	(0.4–4.6)
2930–3199	316	29	0.8	(0.4–1.3)	26	1.0	(0.5–1.9)	3	0.7	(0.2–3.0)
3200–3449	353	35	1.0	reference	25	1.0	reference	5	1.0	reference
3450–3719	338	30	0.9	(0.5–1.6)	22	1.0	(0.5–1.8)	7	1.7	(0.5–5.4)
≥3720	339	46	1.2	(0.7–2.0)	31	1.1	(0.6–2.0)	11	2.6	(0.9–7.8)
Duration of gestation (week)d
<37	111	17	1.0	(0.5–2.0)	9	0.7	(0.3–1.6)	6	2.8	(0.8–9.5)
37–39	493	61	1.0	(0.7–1.4)	50	1.0	(0.7–1.8)	9	0.9	(0.4–2.2)
40–41	1022	108	1.0	reference	81	1.0	reference	20	1.0	reference
>41	40	3	0.8	(0.2–2.7)	2	0.6	(0.1–3.0)	0	-	-
Birth order (index child)
1	708	96	1.0	reference	76	1.0	reference	14	1.0	reference
2	608	62	0.7	(0.5–1.1)	49	0.7	(0.5–1.1)	10	0.9	(0.4–2.1)
3+	365	33	0.6	(0.4–1.0)	19	0.4	(0.3–0.8)	11	1.5	(0.7–3.1)

¹Odds ratios adjusted for age and gender;

²95% CI: 95% Confidence Interval