RhoGDI expression in the ameloblasts of the wild-type, Amel X-/-, Ambn-/-, and Amel X-/-/Ambn-/- mice. Sagittal sections of the incisors from the wild-type (A,E), Amel X-/- (B,F), Ambn-/- (C,G), and Amel X-/-/Ambn-/- mice (D,H) were stained with the RhoGDI antibody as described in Materials & Methods. Note positive staining in the detached ameloblasts of Ambn-/- (C,G) and Amel X-/-/Ambn-/- mice (D,H). Bars = 50 µm. am, ameloblast; od, odontoblast; pu, pulp; si, stratum intermedium; e, enamel; d, dentin; pd, predentin.