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. Author manuscript; available in PMC: 2010 Apr 7.
Published in final edited form as: Circulation. 2009 Mar 23;119(13):1805–1813. doi: 10.1161/CIRCULATIONAHA.108.832972

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Figure 1

Complement depletion protects against AAA development. Increase in AD on day 14 was expressed in mm (A) or percentage (B) over the baseline AD measured prior to elastase perfusion. AAA was defined by an increase in AD of 100% or greater than that measured before elastase perfusion. Western blots demonstrate the decrease in C3 (α and β chains) over time (C) and in the mice pre-treated with CVF (D). Heavy chain serves as control for protein content. Mice were pre-treated with CVF 24 h prior to elastase perfusion or at the time indicated. The increase in AD on day 14 was expressed in mm (E) or percentage (F). The number of animals per time point or treatment type is indicated for each group.