Fig. 2. Restored width of predentin and absence of sporadic unmineralized areas in dentin of DPPcKO mice.
H&E staining of the upper first molars of Dspp+/− mice (a and d), Dspp−/−mice (b and e) with widened predentin and sporadic unmineralized areas in irregular dentin, and DPPcKO-B mice (c and f) with the restored predentin width (still slightly wider than Dspp+/− mice) and absence of the sporadic unmineralized areas. The boarder between predentin and dentin is indicated by line. The unmineralized area is shown by an asterisk, and the dentin-enamel junction is shown by an arrowhead. d, dentin; pd, predentin; p, pulp. Bars in a–c = 200 µm. d–f = 50 µm.
