Table 1.
Diagnostic characteristics of male childhood cancer survivors with subsequent live offspring identified.
| Characteristic | N (%) (n=470) |
|---|---|
| Cancer registry, U.S. State | |
| Atlanta, Georgia | 91 (19.4) |
| Detroit, Michigan | 103 (21.9) |
| Seattle, Washington | 122 (26.0) |
| Utah | 154 (32.8) |
| Year of diagnosis | |
| 1973−1979 | 170 (36.2) |
| 1980−1989 | 229 (48.7) |
| 1990−2000 | 71 (15.1) |
| Age at diagnosis, years | |
| <5 | 35 (7.5) |
| 5−9 | 29 (6.2) |
| 10−14 | 72 (15.3) |
| 15−19 | 334 (71.1) |
| Elapsed years until delivery | |
| <2 | 23 (4.9) |
| 2−5 | 92 (19.6) |
| 6−10 | 151 (32.1) |
| 11−30 | 204 (43.4) |
| Cancer type1 | |
| Leukemia | 51 (10.9) |
| Lymphoma | 118 (25.1) |
| Central nervous system | 47 (10.0) |
| Embryonal2 | 25 (5.3) |
| Malignant bone | 33 (7.0) |
| Soft tissue sarcoma | 42 (8.9) |
| Germ cell/gonadal | 61 (13.0) |
| Thyroid carcinoma | 22 (4.7) |
| Non-basal/squamous cell skin | 36 (7.7) |
| Other carcinoma | 27 (5.7) |
| Other tumors | 8 (1.7) |
| Pelvic primary cancer site | 85 (18.1) |
| Cancer treatment | |
| Chemotherapy only | 66 (14.0) |
| Surgery only | 137 (29.2) |
| Radiotherapy only | 42 (8.9) |
| Chemotherapy+surgery | 62 (13.2) |
| Chemotherapy+radiotherapy | 50 (10.6) |
| Surgery+radiotherapy | 55 (11.7) |
| Chemotherapy+surgery+radiotherapy | 38 (8.1) |
| Other / unknown treatment | 20 (4.3) |
| Any chemotherapy | 216 (46.0) |
| Any surgery | 292 (62.1) |
| Any radiotherapy | 185 (39.4) |
1
Based on the International Classification of Childhood Cancers (Ref 10).
2
Consists of neuroblastoma and related tumors (n=10), embryonal renal (n=13) and hepatic (n=0) tumors, and retinoblastoma (n=2).