Table 2.
Cohort, N (%) |
|||
---|---|---|---|
Characteristic | Childhood cancer (n=892) |
Cervical/genital (n=1006) |
|
Year of diagnosis | |||
1973-1979 | 309 (34.6) | 144 (14.3) | |
1980-1989 | 420 (47.1) | 303 (30.1) | |
1990-2000 | 163 (18.3) | 559 (55.6) | |
Age at diagnosis, years | |||
<5 | 66 (7.4) | - | |
5-9 | 77 (8.6) | - | |
10-14 | 186 (20.9) | 9 (0.9) | |
15-19 | 563 (63.1) | 997 (99.1) | |
Elapsed years until delivery | |||
<2 | 71 (8.0) | 308 (30.6) | |
2-5 | 263 (29.5) | 474 (47.1) | |
6-10 | 263 (29.5) | 175 (17.4) | |
11-30 | 295 (33.1) | 49 (4.9) | |
Cancer type1 | |||
Leukemia | 87 (9.8) | - | |
Lymphoma | 202 (22.7) | - | |
Central nervous system | 89 (10.0) | - | |
Embryonal2 | 47 (5.3) | - | |
Malignant bone | 53 (5.9) | - | |
Soft tissue sarcoma | 65 (7.3) | - | |
Germ cell, gonadal, trophoblastic | 66 (7.4) | - | |
Thyroid carcinoma | 118 (13.2) | - | |
Non-basal/squamous cell skin | 78 (8.7) | - | |
Other carcinoma | 70 (7.9) | 1006 (100.0) | |
Other tumors | 17 (1.9) | - | |
Primary cancer site | |||
Abdomen | 185 (20.7) | 1006 (100.0) | |
Pelvis only | 115 (12.9) | 1006 (100.0) | |
Cancer treatment | |||
Chemotherapy, only | 112 (12.6) | 2 (0.2) | |
Surgery, only | 328 (36.8) | 789 (78.4) | |
Radiotherapy, only | 87 (9.8) | - | |
Chemotherapy+Surgery | 83 (9.3) | - | |
Chemotherapy+Radiotherapy | 86 (9.6) | 1 (0.1) | |
Surgery+Radiotherapy | 111 (12.4) | 2 (0.2) | |
Chemotherapy+Surgery+Radiotherapy | 48 (5.4) | - | |
Other / unknown | 37 (4.2) | 212 (21.1) | |
Any chemotherapy | 329 (36.9) | 3 (0.3) | |
Any surgery | 570 (63.9) | 791 (78.6) | |
Any radiotherapy | 332 (37.2) | 3 (0.3) |
Based on International Classification of Childhood Cancers, 1996 (Ref 2), and includes in-situ lesions: 989 genital tract carcinomas, 4 non-genital tract carcinomas, and 7 skin lesions.
Neuroblastoma and related tumors, embryonal renal and hepatic tumors, and retinoblastoma.