Table 2.
Diagnostic characteristics of female childhood cancer and adolescent cervical/genital cancer cases with subsequent live birth.
| Cohort, N (%) |
|||
|---|---|---|---|
| Characteristic | Childhood cancer (n=892) |
Cervical/genital (n=1006) |
|
| Year of diagnosis | |||
| 1973-1979 | 309 (34.6) | 144 (14.3) | |
| 1980-1989 | 420 (47.1) | 303 (30.1) | |
| 1990-2000 | 163 (18.3) | 559 (55.6) | |
| Age at diagnosis, years | |||
| <5 | 66 (7.4) | - | |
| 5-9 | 77 (8.6) | - | |
| 10-14 | 186 (20.9) | 9 (0.9) | |
| 15-19 | 563 (63.1) | 997 (99.1) | |
| Elapsed years until delivery | |||
| <2 | 71 (8.0) | 308 (30.6) | |
| 2-5 | 263 (29.5) | 474 (47.1) | |
| 6-10 | 263 (29.5) | 175 (17.4) | |
| 11-30 | 295 (33.1) | 49 (4.9) | |
| Cancer type1 | |||
| Leukemia | 87 (9.8) | - | |
| Lymphoma | 202 (22.7) | - | |
| Central nervous system | 89 (10.0) | - | |
| Embryonal2 | 47 (5.3) | - | |
| Malignant bone | 53 (5.9) | - | |
| Soft tissue sarcoma | 65 (7.3) | - | |
| Germ cell, gonadal, trophoblastic | 66 (7.4) | - | |
| Thyroid carcinoma | 118 (13.2) | - | |
| Non-basal/squamous cell skin | 78 (8.7) | - | |
| Other carcinoma | 70 (7.9) | 1006 (100.0) | |
| Other tumors | 17 (1.9) | - | |
| Primary cancer site | |||
| Abdomen | 185 (20.7) | 1006 (100.0) | |
| Pelvis only | 115 (12.9) | 1006 (100.0) | |
| Cancer treatment | |||
| Chemotherapy, only | 112 (12.6) | 2 (0.2) | |
| Surgery, only | 328 (36.8) | 789 (78.4) | |
| Radiotherapy, only | 87 (9.8) | - | |
| Chemotherapy+Surgery | 83 (9.3) | - | |
| Chemotherapy+Radiotherapy | 86 (9.6) | 1 (0.1) | |
| Surgery+Radiotherapy | 111 (12.4) | 2 (0.2) | |
| Chemotherapy+Surgery+Radiotherapy | 48 (5.4) | - | |
| Other / unknown | 37 (4.2) | 212 (21.1) | |
| Any chemotherapy | 329 (36.9) | 3 (0.3) | |
| Any surgery | 570 (63.9) | 791 (78.6) | |
| Any radiotherapy | 332 (37.2) | 3 (0.3) | |
1
Based on International Classification of Childhood Cancers, 1996 (Ref 2), and includes in-situ lesions: 989 genital tract carcinomas, 4 non-genital tract carcinomas, and 7 skin lesions.
2
Neuroblastoma and related tumors, embryonal renal and hepatic tumors, and retinoblastoma.