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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Circulation. 2009 Aug 17;120(9):725–734. doi: 10.1161/CIRCULATIONAHA.108.846501

Figure 1. Seated, standing and orthostatic changes in heart rates and blood pressures before and after propranolol 20mg vs. placebo (Protocol #1).

Figure 1

Heart rate (HR) and systolic blood pressure (SBP) data are presented immediately before (pre), and hourly for 4 hours (4H) following study drug administration for the propranolol 20mg day (“Prop 20”; solid circles) and the placebo day (open squares). Peak HR after standing for a maximum of 10 minutes (Fig 1A), seated HR immediately before standing (Fig 1B) and the changes in HR from sit to stand (Fig 1C) are shown in the top 3 panels. Similarly, the data for standing SBP (Fig 1D), seated SBP (Fig 1E) and the changes in SBP from sit to stand (Fig 1F) are shown in the bottom 3 panels. The error bars represent the standard error of the mean. The ANOVA P values are presented for the overall effect of the study drug over time. bpm – beats per minute; mmHg – millimeters of mercury.