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. Author manuscript; available in PMC: 2010 Jul 23.
Published in final edited form as: J Med Chem. 2009 Jul 23;52(14):4533–4537. doi: 10.1021/jm900380j

Figure 2.

Figure 2

Time dependence of rat nNOS inhibition. WT rat nNOS was incubated with or without 8, and the enzymatic reaction was monitored by the Hb assay for 7 min at room temperature. Only compound 8 with rat nNOS is illustrated; other inhibitors with the three enzymes had the same pattern as compound 8 shown here.