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Examples of perturbation of NA metabolism in autoimmune phenotypes
| Molecule | Phenotype (reference) |
|---|---|
| DNase I | Systemic lupus erythematosus (28) |
| DNase II | Rheumatoid arthritis-like (65) |
| TREX1 (DNase III) | Systemic lupus erythematosus (10) |
| FEN1 (DNase IV) | Systemic lupus erythematosus-like (66) |
| Yaa (TLR7) | Systemic lupus erythematosus (67) |
| HMGB1/RAGE | Systemic lupus erythematosus (68) |
| LL37 | Psoriasis (69) |
| P202 (IfI202) | Systemic lupus erythematosus (61) |
| MDA5 (IFIH1) | Type I diabetes mellitus (70) |
