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Diagrammatic representation of non-canonical Wnt signalling in a mammalian cell. Black arrows indicate the signalling pathway necessary for establishment of planar cell polarity (PCP). Known biochemical interactions are indicated by blue arrows and genetic interactions are shown by red arrows. Ankdr6 is the mammalian homologue of Diego which in Drosophila interacts with Fz, Vang and Pk, but has not been studied in vertebrates.
