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. 2009 Jul 14;94(10):3857–3864. doi: 10.1210/jc.2008-2766

Figure 1.

Figure 1

Abnormal test values for subjects with two or more completed tests. A, Abnormal post 1 mg DST cortisol levels at the initial screening visit. Dotted line represents 1.8 μg/dl (49.6 nmol/liter) diagnostic cutoff level. When available, the dexamethasone levels were all appropriate. Two subjects taking oral contraceptives had cortisol levels of 4.0 and 8.5 μg/dl (110 and 234 nmol/liter); cortisol binding globulin levels were not measured. B, Abnormal UFC values at screening visit (screen) and follow-up (FU). Solid line, Upper normal limit LC-MS/MS assay, 45 μg/24 h (124 nmol/24 h); dashed line, upper normal limit Nichols assay, 77 μg/24 h (213 nmol/24 h). C, Abnormal screening salivary cortisol (Sal F) values by RIA and LC-MS/MS at the screening visit. Solid line, Upper normal limit RIA, 170 ng/dl (4.7 nmol/liter); dashed line, upper normal limit LC-MS/MS, 100 ng/dl (2.8 nmol/liter). D, Follow-up salivary cortisol results in 25 of 58 subjects with RIA and LC-MS/MS split samples. Solid vertical line, upper normal limit RIA, 170 ng/dl (4.7 nmol/liter); dashed line, upper normal limit LC-MS/MS, 100 ng/dl (2.8 nmol/liter).