Fig. 2.

Compiled protein patterns of the CE-MS analysis of urine samples from patients and controls examined in this study. Shown are compiled patterns consisting of all samples from patients with active vasculitis and each of the six control groups. (NC, apparently healthy normal control; DN, diabetic nephropathy.) The molecular mass on a logarithmic scale (0.8–25 kDa; indicated on the left) is plotted against normalized migration time (18–45 min; indicated on the bottom). Signal intensity is encoded by peak height and color. Although the difference in peptides present between apparently healthy controls and the six different chronic renal diseases is evident, distinct biomarkers that can distinguish between AAV and the other chronic renal diseases are not easily identified.