Fig. 3.

Distribution of only the 113 peptides that reveal significant differences between AAV and controls (p value <0.05 after adjustment for multiple testing) shown in the patients with active vasculitis and patients with other chronic renal disease or healthy controls. The molecular mass on a logarithmic scale (0.8–25 kDa; indicated on the left) is plotted against normalized migration time (18–45 min; indicated on the bottom). Signal intensity is encoded by peak height and color. All statistically significant biomarkers from supplemental Table 1 are shown. (NC, normal control; DN, diabetic nephropathy.) When examining only these 113 potential biomarkers, differences between AAV and the other chronic renal diseases become evident.