Figure 3.

RD5 and RD5-like deletions seen in MTBC isolates. This region is susceptible to frequent large deletions. Here we show the genes surrounding PPE38 along with the deleted regions characterised in 5 non-M. tuberculosis MTBC members [22-25,32], along with the deletions detected in the M. tuberculosis whole genome sequences T92 and 94_M4241A. A red arrow indicates the presence and direction of IS6110 at a deletion point. Deletions caused by homologous recombination between PPE39 and PPE40 in M. bovis BCG and 94_M4241A are also shown. Numbering refers to gene nucleotide positions.