Table 4.
Modifications of the effect of ambient PM2.5 concentrations on heart failure admissions
Description | n | % incr. risk# | LCLM^ | UCLM^ | p-value! | |
---|---|---|---|---|---|---|
Individual-level risk factors | ||||||
Age | 85+ | 39,538 | 6.47 | 3.98 | 9.02 | 0.03 |
75-84 | 53,248 | 3.78 | 1.35 | 6.27 | 0.51 | |
65-74 | 36,690 | 2.52 | -0.84 | 6.00 | 0.89 | |
35-64 | 41,026 | 2.76 | 0.36 | 5.22 | (ref) | |
Gender | female | 75,670 | 4.57 | 2.15 | 7.05 | 0.18 |
male | 94,832 | 3.02 | 1.15 | 4.93 | (ref) | |
Atherosclerosis (ICD = 440) | present | 1,389 | 10.66 | -1.79 | 24.69 | 0.29 |
absent | 169,113 | 3.83 | 2.41 | 5.26 | (ref) | |
Previous heart failure admission (ICD = 428) | present | 62,043 | 4.51 | 2.03 | 7.05 | 0.41 |
absent | 108,459 | 3.52 | 1.88 | 5.20 | (ref) | |
Ischemic heart disease (ICD = 410-414) | present | 86,599 | 3.92 | 1.54 | 6.36 | 0.95 |
absent | 83,903 | 3.85 | 2.05 | 5.69 | (ref) | |
Conduction disorder (ICD = 426) | present | 6,238 | 3.66 | -2.29 | 9.96 | 0.94 |
absent | 164,264 | 3.89 | 2.46 | 5.34 | (ref) | |
Diabetes (ICD = 250) | present | 70,986 | 3.72 | 1.31 | 6.18 | 0.80 |
absent | 99,516 | 4.01 | 2.31 | 5.72 | (ref) | |
COPD (ICD = 490-496) | present | 51,736 | 2.48 | -0.05 | 5.07 | 0.10 |
absent | 118,766 | 4.51 | 2.91 | 6.14 | (ref) | |
Area-level risk factors | ||||||
% adults living below poverty level, by census tract | 20%-100% | 57,593 | 2.45 | -0.38 | 5.36 | 0.10 |
7-20% | 58,092 | 4.51 | 1.62 | 7.49 | 0.85 | |
0-7% | 54,817 | 4.79 | 2.61 | 7.01 | (ref) | |
Temporal variables | ||||||
Season | Cool | 94,252 | 4.10 | 1.49 | 6.78 | 0.74 |
Warm | 76,250 | 3.66 | 1.75 | 5.61 | (ref) | |
Year* | 2005 | 34,141 | 2.9 | -0.10 | 6.05 | 0.23 |
2001 | 34,363 | 4.9 | 2.73 | 7.10 | (ref) |
# percent change in risk of heart failure admission per 10 ug/m3 PM2.5 averaged over lags 0-2
*modeled as continuous variable
^ lower and upper 95% confidence limit around risk estimate
! p-value for significance of interaction term