Table 1.
Some examples of different functions and localizations of GAPDH.
| Function/Cellular role | Localization | PTM* | Interaction partner | Reference |
| Apoptosis (Figure 4) | Nucleus | Nitrosylation | Siah | [36] |
| Plasma membrane fusion | Membrane | - | Anion exchanger protein | [37] |
| Microtubule structure and function | Cytoplasm | - | Tubulin | [38] |
| Translational regulation | - | - | 5V and 3VUTR mRNA sequence | [39] |
| Cell transport properties | Secretory vesicles | Phosphorylation | PKCL/E | [40] |
| Transcription control | Nucleus | - | Oct-1 transcription factor + promyelocytic leukemia nuclear bodies |
[41] [42] |
| Nucleus | - | Telomeres | [43] | |
| Intranuclear transport | Nucleus | - | tRNA precursors | [44] |
| Cell proliferation | - | - | Ap4A | [45,46] |
| Nuclear membrane fusion |
Nuclear envelope | - | - | [47] |
*post-translational modification