Table 1.
Top 5 significantly over-represented GO terms of 'molecular function' and 'biological process' in cancer genes vs. non-cancer genes
| GO_ID | # cancer genes | # non-cancer genes | chi-square | p-value | Name | Name space |
| 45786 | 35 | 243 | 260.6 | 1.30E-58 | negative regulation of cell cycle | biological_process |
| 6974 | 34 | 244 | 259.4 | 2.30E-58 | response to DNA damage stimulus | biological_process |
| 50794 | 181 | 97 | 238.8 | 7.20E-54 | regulation of cellular process | biological_process |
| 9719 | 35 | 243 | 235.2 | 4.29E-53 | response to endogenous stimulus | biological_process |
| 6468 | 42 | 236 | 232.8 | 1.49E-52 | protein amino acid phosphorylation | biological_process |
| 4713 | 25 | 253 | 280.7 | 5.37E-63 | protein-tyrosine kinase activity | molecular_function |
| 3677 | 122 | 156 | 195.7 | 1.82E-44 | DNA binding | molecular_function |
| 4672 | 38 | 240 | 193.8 | 4.78E-44 | protein kinase activity | molecular_function |
| 30528 | 95 | 183 | 173.0 | 1.60E-39 | Transcription regulator activity | molecular_function |
| 16733 | 39 | 239 | 154.8 | 1.54E-35 | phosphotransferase activity, alcohol group as acceptor | molecular_function |