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. Author manuscript; available in PMC: 2010 Jun 15.
Published in final edited form as: Clin Cancer Res. 2009 Jun 9;15(12):4199–4206. doi: 10.1158/1078-0432.CCR-08-2257

Table 2.

Functions of treatment-regulated genes

Function Molecules
Molecular and cellular functions
  Cell cycle MAD2L1 KIF23 DKFZP762E1312 CDCA5 AURKA CXCL12 FOXM1 XPC CIT CHEK1 CDKN1A RRM2B
  DNA replication, recombination, and repair KIF23 HMGB2 DKFZP762E1312 CDCA5 RFC3 CXCL12 MMP2 CIT CDKN1A MAD2L1 AURKA GUCY1A3 FOXM1 XPC CHEK1 UNG
  Cell death MAD2L1 AURKA VCAM1 FOXM1 CXCL12 MMP2 CIT XPC CHEK1 CDKN1A RRM2B UNG
Disease and disorder
  Cancer HMGB2 KIF23 DKFZP762E1312 ENPP2 VCAM1 CXCL12 MMP2 CDKN1A RRM2B MAD2L1 AURKA KIAA0101 FOXM1 XPC CHEK1 UNG
  Gastrointestinal disease MAD2L1 HMGB2 ENPP2 VCAM1 AURKA CXCL12 CHEK1 CDKN1A RRM2B UNG