Table 1.
Infertility treatment variables and patients characteristics of smokers and non-smokers undergoing COH and IUI for infertility treatment
| Nonsmoking | Smoking | P | |
|---|---|---|---|
| No. patients | 679 | 206 | |
| No. cycles | 1803 | 515 | |
| Age (years) | 27.1 ± 3.6 | 27.6 ± 3.7 | ns |
| Smoking/day(Packs) | 0 | 0.8 ± 0.3 | |
| Primary infertility (%) | 448 (66%) | 125 (61%) | ns |
| Number of male partner smokers | 182 (26.8%) | 129 (62.6%) | 0.000 |
| Duration of infertility (yrs) | 1.4 ± 1.0 | 1.5 ± 1.1 | ns |
| Day 3 FSH (IU/L) | 6.3 ± 3.4 | 6.6 ± 2.7 | ns |
| Mean no. cycles/patient | 2.2 ± 1.4 | 2.1 ± 1.3 | 0.08 |
| Duration of Gn stimulation | 8.5 ± 3.2 | 8.5 ± 3.4 | ns |
| Mean Gn per cycle (IU) | 949 ± 526 | 1016 ± 556 | 0.016 |
| No. of follicles ≥14 mm on hCG day | 2.4 ± 1.9 | 2.5 ± 1.8 | ns |
| E2 level on hCG day (pmol/L) | 2379 ± 1867 | 2347 ± 1970 | ns |
| Endometrial thickness on hCG day (mm) | 9.3 ± 2.0 | 8.9 ± 2.1 | 0.016 |
| Clinical pregnancies (n) | 286 | 84 | |
| Pregnancy rate/cycle | 15.8% | 16.3% | ns |
| Early abortions (<12wk) (% of clinical pregnancies) | 39 (13.6%) | 10 (11.9%) | ns |
| EUP (% of clinical pregnancies) | 5(1.7%) | 1 (1.2%) | ns |
Gn-gonadotropin
EUP-extra uterine pregnancy