Figure 3.

Distribution of mCry1 and mCry2 in the mouse brain. Mouse coronal brain sections (made at zeitgeber time = ZT6) passing through the SCN were probed with mCry1 and mCry2 antisense RNA. Both Cry1 and Cry2 are abundant in all cerebral cortical layers but are particularly abundant in the pyramidal cell layer of the hippocampus (H), the granular cell layer of dentate gyrus (DG), and the pyramidal cell layer of the piriform cortex (PFC). Note that the strongest signal of Cry1 was observed in the SCN where the Cry2 signal is marginal. (Bar = 1 mm.)