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. Author manuscript; available in PMC: 2009 Oct 8.
Published in final edited form as: Am J Med Genet A. 2005 Oct 1;138A(2):133–140. doi: 10.1002/ajmg.a.30952

Figure 5. Location of deafness-associated mutations in the tRNASer(UCN) and adjacent COI.

Figure 5

Arrows indicate the position of the T7510C, T7511C and 7472insC mutations in the tRNASer(UCN) and the A7445G and G7444A mutation in the precursor of this tRNA and adjacent sequence of COI from wild-type (WT) and mutant (MT). The processing site for the 3-end of tRNASer(UCN) precursor, determined by and 3’-endonuclease [Guan et al., 1998], was indicated by arrow.