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(a) MTRasy versus frequency offset of the presaturation pulse for five liposome samples (diameter ~ 80 nm), each encapsulating a different concentration of TmDOTA from 100 to 400 mM. (b) The frequency offset, Δωm, at which MTRasy maximizes as a function of the initial TmDOTA concentration. The dashed line represents a linear fit to the three samples with the lowest initial [TmDOTA].
