Table 2.

Exchange Rate Analysis of MTR_asy versus T_sat for Three Liposome Samples Using Three Different Methods Outlined in the Experimental Section

method	sample	$\stackrel{‒}{k_{lw}}$ (s-1)	kwl (s-1)	α	T1wa (s)	Plb (μm/s)
(i)	99 nm	194	0.89	0.85	2.11
	199 nm	94	0.43	0.84	2.20	0.99 ± 0.21
	536 nm	12	0.056	0.84	2.65
(ii)	99 nm	174	0.80	0.93
	199 nm	88	0.40	0.95	1.85	0.89 ± 0.21
	536 nm	13	0.062	0.99
(iii)	99 nm	221	1.02	0.88
	199 nm	93	0.43	0.95	2.03	1.11 ± 0.14
	536 nm	13	0.059	0.99

^aT_1w is calculated for each sample in method (i); it is treated as a single fit parameter in methods (ii) and (iii).

^bErrors in permeability are 95% confidence intervals in the linear coefficients of exchange rates versus ΣS/V.