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. Author manuscript; available in PMC: 2010 Jan 10.
Published in final edited form as: Mol Cell. 2009 Jul 10;35(1):48–57. doi: 10.1016/j.molcel.2009.05.023

Figure 6. TLR4/IKKε and TLR2/CaMKII pathways regulate distinct subsets of proinflammatory target genes.

Figure 6

(A-D) ChIP assay for NCoR on the indicated promoters in BMDM transfected with siCTL, siIKKε or siCaMKII siRNAs and stimulated with LPS for 20min or Pam3 for 5 min. (E, F) Effect of LPS and Pam3 treatment of BMDM on NCoR occupancy and mRNA induction of dtx2 (E) and sphk1 (F). (G,H) Induction of sphk1 (G) and dtx2 (H) mRNA in BMDM transfected with siCTL or siCaMKIIγ siRNAs and stimulated with Pam3 for 2hrs. *p<0.05 versus treated siCTL sample. Errors bars represent SD.