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. Author manuscript; available in PMC: 2010 Jul 15.
Published in final edited form as: Bioorg Med Chem. 2009 Jun 22;17(14):5027–5037. doi: 10.1016/j.bmc.2009.05.070

Figure 2. Structures of the four VIM-2 inhibitors found from HTS efforts.

Figure 2

Mitoxantrone and pCMB were found active in LOPAC screening. Compounds 1 and 2 are sulfonyl-triazoles found from click-chemistry library screening.