Table 1.

Interactions between dopamine and adenosine receptor antagonists.

	Adenosine receptor antagonist
	Non-selective	A1	A2A
CONCURRENT FR5/FREE CHOW
D2 receptor antagonist	Reversal	No reversal	Reversal	Farrar et al. (2007), Salamone et al. (2009), Worden et al. (2009)
D1 receptor antagonist	–	No reversal	Partial reversal1	Worden et al. (2009)1, Nunes et al. (2009)2
T-MAZE WITH BARRIER
D2 receptor antagonist	Reversal	No reversal	Reversal	Mott et al. (2009), Pardo (2009)3

¹There was a mild increase in lever pressing in ecopipam-treated rats that received the A_2A antagonist MSX-3, but no reversal of the chow intake effect of the D₁ antagonist.

²Data from Nunes et al. (2009).

³Data from Pardo (2009), unpublished masters thesis, University of Jaume I.