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. Author manuscript; available in PMC: 2010 Oct 2.
Published in final edited form as: Cell. 2009 Oct 2;139(1):149–160. doi: 10.1016/j.cell.2009.07.034

Figure 6. Overexpression of Activated d4E-BP Extends Lifespan in a Nutrient Dependent Manner in Drosophila.

Figure 6

(A-D) Male and female flies overexpressing d4E-BPLLs (4E-BPs) using armadillo (arm) GAL4 strain extends lifespan on high nutrition (5%YE) but not under DR (0.25% YE).

(A) Survival of male flies on high nutrition.

(B) Female flies on high nutrition.

(C) Male flies under DR.

(D) Female flies under DR. ‘+’ is the Benzer Lab w1118 strain, into which each of these lines was outcrossed 6 times. P values were obtained by comparing the survival curves with GraphPad Prism Software using the longest lived control. (Statistical analyses with replicates are shown in Table S7)