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. 2009 Aug 7;66(21):3403–3420. doi: 10.1007/s00018-009-0095-2

Table 2.

Summary of key transcription factors discussed in this review

Name of transcription factor Explanation Gene family
Oct4 Octamer binding transcription factor 4 POU (Pit, Oct, Unc) domain transcription factor
Sox2 SRY (sex determining region Y)-related HMG box 2 transcription factor HMG (High Mobility Group) of DNA-binding proteins
Nanog Named after ‘Tir na nOg’ (Celtic mythology = land of the ever young) Homeodomain transcription factor
Cdx2 Caudal type homeobox transcription factor 2 Homeodomain transcription factor
Gata6 Binding of (G/A)GATA(A/T) DNA consensus GATA family of transcription factors