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. 2009 Aug 28;18(9):1219–1237. doi: 10.1007/s11136-009-9530-y

Table 5.

Responsiveness indices: declined and unchanged groups based on “How Parkinson’s disease affects you on a day-to-day basis?”a

Baseline mean in declined group (SD) Average change in declined group (SD) Average change in the unchanged group (SD) Effect size statistic SRM Guyatt F (P value)
SF-36 v. 1.0 (range: 0–100, where 100 is best quality of life)
  Physical Function 70.0 (26.7) −22.8 (22.0) −1.6 (22.9) −0.85b −1.04 −0.99 9.54 (0.004)
  Role Limitations—Physical 47.5 (41.3) −16.3 (43.9) 6.9 (29.4) −0.39d −0.37 −0.55 4.22 (0.05)
  Role Limitations—Emotional 90.0 (30.8) −11.7 (49.9) −2.9 (43.7) −0.38d −0.23 −0.27 0.38 (0.54)
  Pain 68.4 (24.5) −1.5 (30.0) 2.2 (26.5) −0.06 −0.05 −0.06 0.18 (0.67)
  Emotional Well-Being 77.8 (13.8) −1.2 (19.0) −3.0 (18.9) −0.09 −0.06 −0.06 0.09 (0.76)
  Energy 66.3 (17.2) −19.5 (22.3) −3.0 (23.7) −1.13b −0.87 −0.82 5.44 (0.03)
  General Health 69.8 (10.4) −18.0 (17.7) −4.1 (13.8) −1.72b −1.02 −1.31 8.31 (0.006)
  Social Function 81.9 (24.5) −12.5 (39.5) 1.1 (28.2) −0.51c −0.32 −0.44 1.72 (0.20)
SF-36 composite scores (T-scores)
  Physical Health (PCS) 41.3 (8.9) −7.7 (10.1) 0.8 (6.9) −0.86b −0.76 −1.11 10.51 (0.002)
  Mental Health (MCS) 55.5 (8.5) −2.5 (10.7) −1.6 (10.8) −0.29d −0.23 −0.22 0.08 (0.78)
PDQUALIF (range: 0–100, where 100 is best quality of life)
  Social/Role Function 69.4 (23.9) −19.1 (21.7) −1.7 (21.1) −0.80b −0.88 −0.91 6.98 (0.01)
  Self-Image and Sexuality 69.5 (22.9) −5.9 (19.6) 7.8 (19.3) −0.26d −0.30 −0.31 5.18 (0.03)
  Sleep 72.5 (29.0) −10.0 (23.8) −12.8 (28.9) −0.35d −0.42 −0.35 0.12 (0.73)
  Outlook 74.7 (18.3) −3.8 (18.5) 1.4 (19.1) −0.21d −0.21 −0.20 0.79 (0.38)
  Physical Function 73.0 (19.9) −3.3 (19.7) −11.1 (13.5) −0.16 −0.17 −0.24 2.32 (0.14)
  Independence 84.4 (31.9) −20.6 (34.5) −1.14 (32.0) −0.65c −0.60 −0.64 3.61 (0.07)
  Urinary Function 43.1 (31.0) 2.5 (36.9) 0.6 (44.4) −0.08 0.07 0.06 0.02 (0.88)
Total score 69.5 (17.2) −8.6 (15.2) −2.4 (17.7) −0.50c −0.57 −0.49 1.44 (0.24)
PDQ-39 (range: 0–100, where 100 is best quality of life)
  Mobility 75.4 (26.4) −16.9 (26.1) 5.4 (16.2) −0.64c −0.65 −1.04 11.62 (0.002)
  Activities of Daily Living 68.3 (27.5) −13.5 (27.1) 2.0 (15.1) −0.49d −0.50 −0.89 5.59 (0.02)
  Emotional Well-Being 85.0 (20.9) −7.1 (14.3) −1.5 (15.2) −0.34d −0.49 −0.47 1.51 (0.23)
  Stigma 80.9 (27.8) 4.7 (22.2) 10.9 (21.1) 0.17 0.21 0.22 0.88 (0.35)
  Social Support 88.3 (27.1) 0.4 (34.0) 2.7 (18.2) 0.02 0.01 0.02 0.08 (0.78)
  Cognitions 74.1 (17.4) −7.2 (21.8) −1.4 (12.9) −0.41d −0.33 −0.56 1.18 (0.29)
  Communication 83.1 (23.5) −14.2 (16.2) 2.2 (21.4) −0.60c −0.88 −0.66 7.8 (0.008)
  Bodily Discomfort 63.8 (25.6) −7.5 (23.6) 2.5 (20.6) −0.29d −0.32 −0.36 2.22 (0.14)
Total score 77.4 (19.7) −7.7 (15.9) 2.9 (11.1) −0.39d −0.48 −0.69 6.44 (0.02)

aDeclined group declined at least one category from baseline to follow-up (n = 20); Unchanged group remained in the same category at follow-up (n = 23). All the scales scored on a 0 (worst) to 100 (best) possible range, except for the SF-36 PCS and MCS, which are T-scores (mean = 50, SD = 10) calculated against a reference population

bLarge effect size (effect size greater than or equal to 0.80)

cMedium effect size (effect size between 0.20 and 0.49)

dSmall effect size (effect size between 0.50 and 0.79)