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. Author manuscript; available in PMC: 2010 Oct 15.
Published in final edited form as: Biochem Pharmacol. 2009 May 27;78(8):966–973. doi: 10.1016/j.bcp.2009.05.025

Fig. 3. Bz-423 activates Bax and Bak.

Fig. 3

(A) Ramos cells were treated with Bz-423 (10 µM) for the indicated times followed by cell fractionation. Cytosolic and mitochondrial Bax and cytochrome c was detected by immunoblot. (B) Ramos cells were treated with vehicle or Bz-423 (10 µM, 12 h) followed by detection of activated N-terminal Bax or Bak by immunofluorescence microscopy.