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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: Int J Gynecol Cancer. 2009 May;19(4):531–539. doi: 10.1111/IGC.0b013e3181a41613

FIGURE 7.

FIGURE 7

Figure 7. Putative precursor lesions of ovarian carcinoma in hens. A, Section of hen ovary with non-tumor abnormalities showing transformation of the ovarian surface epithelial layer from single columnar epithelial cells to a rounded phenotype with mitotic nuclei consistent with a malignant potential. Inset showing magnified (120×) view of transformed and normal surface epithelial cells. B, Section of hen ovary with non-tumor abnormalities. Marked epithelial dysplasia is seen in the surface layer with stromal invaginations. C, Section of hen ovary with non-tumor abnormalities showing inclusion cysts in the cortex beneath the ovarian surface epithelium containing epithelial cells of rounded phenotype. H &E, 40×.