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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Curr Opin Microbiol. 2009 Jul 14;12(4):394–400. doi: 10.1016/j.mib.2009.06.010

Figure 2. Progression of sporozoite invasion of the salivary gland.

Figure 2

1) The sporozoite attaches to the basal lamina; 2) Sporozoite passage to the space between the basal lamina and the basal epithelial cell plasma membrane, a process associated with the loss of the sporozoite’s thick coat; 3) Penetration of the basal plasma membrane; the sporozoite resides within a vesicle; 4) Release of the sporozoite from the surrounding membrane by an unknown mechanism; 5) Invasion of the apical membrane and entry into the secretory cavity; 6) Sporozoites are released from the surrounding membrane by an unknown mechanism; 7) Sporozoites assemble into bundles within the secretory cavity; and 8) A small number of sporozoites enter the secretory duct by an unknown mechanism. BL: Basal Lamina; DW: Duct wall; N: nucleus; n: nucleolus; PM: Plasma membrane; SC: Secretory cavity. Modified from reference [•5].